Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack
نویسندگان
چکیده
منابع مشابه
Clopidogrel with aspirin in minor stroke or transient ischemic attack.
To the Editor: Wang et al. (July 4 issue)1 report the results of the Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events (CHANCE) trial, which showed that in patients with transient ischemic attack (TIA) or minor stroke who can be treated within 24 hours after the onset of symptoms, the combination of clopidogrel and aspirin was superior to aspirin alone for reducin...
متن کامل100 - Transient Ischemic Attack and Acute Ischemic Stroke
The yearly incidence of TIA in the United States has been estimated to be approximately 200,000 to 500,000 but may be higher because of the high frequency of underreporting of these events by medical professionals. The annual incidence of TIA may be less and the annual incidence of stroke may be higher if the tissue-based definition were applied to all patients evaluated for TIA. It has been es...
متن کاملClopidogrel With Aspirin in Acute Minor Stroke or Transient Ischemic Attack (CHANCE) Trial: One-Year Outcomes.
BACKGROUND The Clopidogrel in High-risk patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial showed that the combined treatment of clopidogrel and aspirin decreases the 90-day risk of stroke without increasing hemorrhage in comparison with aspirin alone, but provided insufficient data to establish whether the benefit persisted over a longer period of time beyond the trial ter...
متن کاملClopidogrel with aspirin in acute minor stroke or transient ischemic attack.
BACKGROUND Stroke is common during the first few weeks after a transient ischemic attack (TIA) or minor ischemic stroke. Combination therapy with clopidogrel and aspirin may provide greater protection against subsequent stroke than aspirin alone. METHODS In a randomized, double-blind, placebo-controlled trial conducted at 114 centers in China, we randomly assigned 5170 patients within 24 hour...
متن کاملTicagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack.
BACKGROUND Ticagrelor may be a more effective antiplatelet therapy than aspirin for the prevention of recurrent stroke and cardiovascular events in patients with acute cerebral ischemia. METHODS We conducted an international double-blind, controlled trial in 674 centers in 33 countries, in which 13,199 patients with a nonsevere ischemic stroke or high-risk transient ischemic attack who had no...
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ژورنال
عنوان ژورنال: Circulation
سال: 2017
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.116.024913